Hydra regeneration and epitheliopeptides
نویسندگان
چکیده
منابع مشابه
A Comprehensive Transcriptomic and Proteomic Analysis of Hydra Head Regeneration
The cnidarian freshwater polyp Hydra sp. exhibits an unparalleled regeneration capacity in the animal kingdom. Using an integrative transcriptomic and stable isotope labeling by amino acids in cell culture proteomic/phosphoproteomic approach, we studied stem cell-based regeneration in Hydra polyps. As major contributors to head regeneration, we identified diverse signaling pathways adopted for ...
متن کاملHead regeneration in wild-type hydra requires de novo neurogenesis.
Because head regeneration occurs in nerve-free hydra mutants, neurogenesis was regarded as dispensable for this process. Here, in wild-type hydra, we tested the function of the ParaHox gsx homolog gene, cnox-2, which is a specific marker for bipotent neuronal progenitors, expressed in cycling interstitial cells that give rise to apical neurons and gastric nematoblasts (i.e. sensory mechanorecep...
متن کاملSlow-cycling stem cells in hydra contribute to head regeneration
Adult stem cells face the challenge of maintaining tissue homeostasis by self-renewal while maintaining their proliferation potential over the lifetime of an organism. Continuous proliferation can cause genotoxic/metabolic stress that can compromise the genomic integrity of stem cells. To prevent stem cell exhaustion, highly proliferative adult tissues maintain a pool of quiescent stem cells th...
متن کاملWhy polyps regenerate and we don't: towards a cellular and molecular framework for Hydra regeneration.
The basis for Hydra's enormous regeneration capacity is the "stem cellness" of its epithelium which continuously undergoes self-renewing mitotic divisions and also has the option to follow differentiation pathways. Now, emerging molecular tools have shed light on the molecular processes controlling these pathways. In this review I discuss how the modular tissue architecture may allow continuous...
متن کاملHydra
What is Hydra? Hydra is a member of the animal phylum Cnidaria. This phylum includes corals, sea anemones and jellyfish. While most cnidarians are marine, Hydra is unusual in that it lives exclusively in fresh water. Hydra was first described by Antoni van Leeuwenhoek (1632– 1723) in a letter he sent to the Royal Society on Christmas day, 1702. The letter included a red chalk drawing of Hydra o...
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ژورنال
عنوان ژورنال: Developmental Dynamics
سال: 2003
ISSN: 1058-8388,1097-0177
DOI: 10.1002/dvdy.10221